Center for Immunity and Inflammation

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   Ricardo Rajsbaum, PHD, MS

Assoc Prof and Director, Ctr for Virus Host Innate Immunity
Department of Medicine

Center for Immunity and Inflammation
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Ricardo Rajsbaum, PhD. Dr. Rajsbaum received his BSc from the National Autonomous University of Mexico (UNAM), in Mexico City, and his MSc from the Weizmann Institute of Science, Israel. He then received his Ph.D. from the National Institute for Medical Research, London, UK, in the laboratory of Anne O???Garra, and completed his postdoctoral training at Mount Sinai School of Medicine, New York in the laboratory of Adolfo Garcia-Sastre. Dr Rajsbaum joined the University of Texas Medical Branch (UTMB) as faculty in 2014 where he first developed his independent research program. While at UTMB Dr Rajsbaum???s lab made important contributions on the regulation of cytokine expression in immune cells, Pattern Recognition Receptor (TLR and RIG-I-like receptors) signaling, regulation and function of type-I Interferons (IFNs), and virus???host interactions, with a specific focus on the role of ubiquitin and TRIM E3-ubiquitin ligases in innate antiviral function. The lab identified novel mechanisms used by viruses to enhance their replication, by targeting host factors that can normally have antiviral functions. Dr. Rajsbaum's lab moved to Rutgers in May 2022 to develop the new Center for Virus-Host-Innate Immunity (CVHII). Current research is focused on the role of the E3-ubiquitin ligase TRIM6 during infections with highly pathogenic viruses (Ebola, Influenza, SARS-CoV-2), the role of the ubiquitin system in promoting replication of flaviviruses (Zika, dengue, West Nile), and SARS-CoV-2 replication, and the role of unanchored polyubiquitin chains in regulation of innate immune signaling. The lab uses biochemical and in vitro approaches to understand molecular mechanisms as well as animal models to study physiological relevance. The lab is a highly collaborative and inclusive environment and extremely values diversity career development.


PHD, 2009, MCR National Institute for Medical Research (NIMR)
MS, 1999, Weizmann Institute of Sciences
BS, 1996, National Autonomous University of Mexico (UNAM)